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Proposing a minimal set of metrics and methods to predict probabilities of amyloidosis disease and onset age in individuals
Many amyloid-driven pathologies have both genetic and stochastic components where assessing risk of disease development requires a multifactorial assessment where many of the variables are poorly understood. Risk of transthyretin-mediated amyloidosis is enhanced by age and mutation of the transthyre...
Autores principales: | Criddle, Richard S., Lin, Hsien-Jung L., James, Isabella, Park, Ji Sun, Hansen, Lee D., Price, John C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746394/ https://www.ncbi.nlm.nih.gov/pubmed/33203794 http://dx.doi.org/10.18632/aging.202208 |
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