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Off-label use of chloroquine, hydroxychloroquine, azithromycin and lopinavir/ritonavir in COVID-19 risks prolonging the QT interval by targeting the hERG channel

Coronavirus disease-2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), poses an enormous challenge to the medical system, especially the lack of safe and effective COVID-19 treatment methods, forcing people to look for drugs that may have therapeutic effects as...

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Detalles Bibliográficos
Autores principales: Zequn, Zheng, Yujia, Wu, Dingding, Qian, Jiangfang, Lian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746509/
https://www.ncbi.nlm.nih.gov/pubmed/33345848
http://dx.doi.org/10.1016/j.ejphar.2020.173813