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Topical application of human-derived Ig isotypes for the control of acute respiratory infection evaluated in a human CD89-expressing mouse model

Recurrent and persistent airway infections remain prevalent in patients with primary immunodeficiency (PID), despite restoration of serum immunoglobulin levels by intravenous or subcutaneous plasma-derived IgG. We investigated the effectiveness of different human Ig isotype preparations to protect m...

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Detalles Bibliográficos
Autores principales: Koernig, Sandra, Campbell, Ian K., Mackenzie-Kludas, Charley, Schaub, Alexander, Loetscher, Marius, Ching Ng, Wy, Zehnder, Roland, Pelczar, Pawel, Sanli, Ildem, Alhamdoosh, Monther, Ng, Milica, Brown, Lorena E., Käsermann, Fabian, Vonarburg, Cédric, Zuercher, Adrian W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746524/
https://www.ncbi.nlm.nih.gov/pubmed/31105268
http://dx.doi.org/10.1038/s41385-019-0167-z