Cargando…

Primary Extracellular Matrix Enables Long-Term Cultivation of Human Tumor Oral Mucosa Models

3D tumor models clearly outperform 2D cell cultures in recapitulating tissue architecture and drug response. However, their potential in understanding treatment efficacy and resistance development should be better exploited if also long-term effects of treatment could be assessed in vitro. The main...

Descripción completa

Detalles Bibliográficos
Autores principales: Gronbach, Leonie, Jurmeister, Philipp, Schäfer-Korting, Monika, Keilholz, Ulrich, Tinhofer, Ingeborg, Zoschke, Christian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746540/
https://www.ncbi.nlm.nih.gov/pubmed/33344431
http://dx.doi.org/10.3389/fbioe.2020.579896