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Primary Extracellular Matrix Enables Long-Term Cultivation of Human Tumor Oral Mucosa Models
3D tumor models clearly outperform 2D cell cultures in recapitulating tissue architecture and drug response. However, their potential in understanding treatment efficacy and resistance development should be better exploited if also long-term effects of treatment could be assessed in vitro. The main...
Autores principales: | Gronbach, Leonie, Jurmeister, Philipp, Schäfer-Korting, Monika, Keilholz, Ulrich, Tinhofer, Ingeborg, Zoschke, Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746540/ https://www.ncbi.nlm.nih.gov/pubmed/33344431 http://dx.doi.org/10.3389/fbioe.2020.579896 |
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