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Cryo-EM structure of the inhibited (10S) form of myosin II

Myosin II is the motor protein responsible for contractility in muscle and nonmuscle cells(1). The molecule has two identical heads attached to an elongated tail, and can exist in two conformations: 10S and 6S, named for their sedimentation coefficients(2,3). The 6S conformation has an extended tail...

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Detalles Bibliográficos
Autores principales: Yang, Shixin, Tiwari, Prince, Lee, Kyoung Hwan, Sato, Osamu, Ikebe, Mitsuo, Padrón, Raúl, Craig, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746622/
https://www.ncbi.nlm.nih.gov/pubmed/33268893
http://dx.doi.org/10.1038/s41586-020-3007-0