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Cryo-EM structure of the inhibited (10S) form of myosin II
Myosin II is the motor protein responsible for contractility in muscle and nonmuscle cells(1). The molecule has two identical heads attached to an elongated tail, and can exist in two conformations: 10S and 6S, named for their sedimentation coefficients(2,3). The 6S conformation has an extended tail...
Autores principales: | Yang, Shixin, Tiwari, Prince, Lee, Kyoung Hwan, Sato, Osamu, Ikebe, Mitsuo, Padrón, Raúl, Craig, Roger |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746622/ https://www.ncbi.nlm.nih.gov/pubmed/33268893 http://dx.doi.org/10.1038/s41586-020-3007-0 |
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