Hyperpolarized mitochondria accumulate in Drosophila Hipk-overexpressing cells to drive tumor-like growth

Both functional and dysfunctional mitochondria are known to underlie tumor progression. Here, we establish use of the proto-oncogene Drosophila Homeodomain-interacting protein kinase (Hipk) as a new tool to address this paradox. We find that, in Hipk-overexpressing tumor-like cells, mitochondria acc...

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Detalles Bibliográficos
Autores principales: Wong, Kenneth Kin Lam, Liao, Jenny Zhe, Shih, Claire R. Y., Harden, Nicholas, Verheyen, Esther M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746665/
https://www.ncbi.nlm.nih.gov/pubmed/33199523
http://dx.doi.org/10.1242/jcs.250944

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746665/
https://www.ncbi.nlm.nih.gov/pubmed/33199523
http://dx.doi.org/10.1242/jcs.250944

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