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The neuroprotective effects of activated α7 nicotinic acetylcholine receptor against mutant copper–zinc superoxide dismutase 1-mediated toxicity

Amyotrophic lateral sclerosis (ALS) is a fatal neurodegenerative disease characterized by the selective and progressive loss of motor neurons. Although many drugs have entered clinical trials, few have shown effectiveness in the treatment of ALS. Other studies have shown that the stimulation of α7 n...

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Detalles Bibliográficos
Autores principales: Ito, Taisei, Inden, Masatoshi, Ueda, Tomoyuki, Asaka, Yuta, Kurita, Hisaka, Hozumi, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746719/
https://www.ncbi.nlm.nih.gov/pubmed/33335227
http://dx.doi.org/10.1038/s41598-020-79189-y