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Effects of activation of the LINE-1 antisense promoter on the growth of cultured cells

Long interspersed element 1 (LINE-1, or L1) is a retrotransposon that constitutes ~ 17% of the human genome. Although ~ 6000 full-length L1s spread throughout the human genome, their biological significance remains undetermined. The L1 5′ untranslated region has bidirectional promoter activity with...

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Detalles Bibliográficos
Autores principales: Honda, Tomoyuki, Nishikawa, Yuki, Nishimura, Kensuke, Teng, Da, Takemoto, Keiko, Ueda, Keiji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746726/
https://www.ncbi.nlm.nih.gov/pubmed/33335226
http://dx.doi.org/10.1038/s41598-020-79197-y