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Structure, membrane topology and influence of cholesterol of the membrane proximal region: transmembrane helical anchor sequence of gp41 from HIV

During the first steps of HIV infection the Env subunit gp41 is thought to establish contact between the membranes and to be the main driver of fusion. Here we investigated in liquid crystalline membranes the structure and cholesterol recognition of constructs made of a gp41 external region carrying...

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Detalles Bibliográficos
Autores principales: Aisenbrey, Christopher, Rifi, Omar, Bechinger, Burkhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746737/
https://www.ncbi.nlm.nih.gov/pubmed/33335248
http://dx.doi.org/10.1038/s41598-020-79327-6