Analyzing In Silico the Relationship Between the Activation of the Edema Factor and Its Interaction With Calmodulin

Molecular dynamics (MD) simulations have been recorded on the complex between the edema factor (EF) of Bacilllus anthracis and calmodulin (CaM), starting from a structure with the orthosteric inhibitor adefovir bound in the EF catalytic site. The starting structure has been destabilized by alternate...

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Detalles Bibliográficos
Autores principales: Pitard, Irène, Monet, Damien, Goossens, Pierre L., Blondel, Arnaud, Malliavin, Thérèse E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746812/
https://www.ncbi.nlm.nih.gov/pubmed/33344505
http://dx.doi.org/10.3389/fmolb.2020.586544

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746812/
https://www.ncbi.nlm.nih.gov/pubmed/33344505
http://dx.doi.org/10.3389/fmolb.2020.586544

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