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Transient Receptor Potential Melastatin 8 (TRPM8) Channel Regulates Proliferation and Migration of Breast Cancer Cells by Activating the AMPK-ULK1 Pathway to Enhance Basal Autophagy

The calcium-permeable cation channel TRPM8 (transient receptor potential melastatin 8) is a member of the TRP superfamily of cation channels that is upregulated in various types of cancer with high levels of autophagy, including prostate, pancreatic, breast, lung, and colon cancers. Autophagy is clo...

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Detalles Bibliográficos
Autores principales: Huang, Yuan, Li, Shi, Jia, Zhenhua, Zhao, Weiwei, Zhou, Cefan, Zhang, Rui, Ali, Declan William, Michalak, Marek, Chen, Xing-Zhen, Tang, Jingfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746826/
https://www.ncbi.nlm.nih.gov/pubmed/33344232
http://dx.doi.org/10.3389/fonc.2020.573127