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Transient Receptor Potential Melastatin 8 (TRPM8) Channel Regulates Proliferation and Migration of Breast Cancer Cells by Activating the AMPK-ULK1 Pathway to Enhance Basal Autophagy
The calcium-permeable cation channel TRPM8 (transient receptor potential melastatin 8) is a member of the TRP superfamily of cation channels that is upregulated in various types of cancer with high levels of autophagy, including prostate, pancreatic, breast, lung, and colon cancers. Autophagy is clo...
Autores principales: | Huang, Yuan, Li, Shi, Jia, Zhenhua, Zhao, Weiwei, Zhou, Cefan, Zhang, Rui, Ali, Declan William, Michalak, Marek, Chen, Xing-Zhen, Tang, Jingfeng |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746826/ https://www.ncbi.nlm.nih.gov/pubmed/33344232 http://dx.doi.org/10.3389/fonc.2020.573127 |
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