A Highly Expressing, Soluble, and Stable Plant-Made IgG Fusion Vaccine Strategy Enhances Antigen Immunogenicity in Mice Without Adjuvant

Therapeutics based on fusing a protein of interest to the IgG Fc domain have been enormously successful, though fewer studies have investigated the vaccine potential of IgG fusions. In this study, we systematically compared the key properties of seven different plant-made human IgG1 fusion vaccine c...

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Detalles Bibliográficos
Autores principales: Diamos, Andrew G., Pardhe, Mary D., Sun, Haiyan, Hunter, Joseph G. L., Kilbourne, Jacquelyn, Chen, Qiang, Mason, Hugh S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746858/
https://www.ncbi.nlm.nih.gov/pubmed/33343565
http://dx.doi.org/10.3389/fimmu.2020.576012

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746858/
https://www.ncbi.nlm.nih.gov/pubmed/33343565
http://dx.doi.org/10.3389/fimmu.2020.576012

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