Ad-CD40L mobilizes CD4 T cells for the treatment of brainstem tumors

BACKGROUND: Diffuse midline glioma, formerly DIPG (diffuse intrinsic pontine glioma), is the deadliest pediatric brainstem tumor with median survival of less than one year. Here, we investigated (i) whether direct delivery of adenovirus-expressing cluster of differentiation (CD)40 ligand (Ad-CD40L)...

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Detalles Bibliográficos
Autores principales: Wongthida, Phonphimon, Schuelke, Matthew R, Driscoll, Christopher B, Kottke, Timothy, Thompson, Jill M, Tonne, Jason, Stone, Cathy, Huff, Amanda L, Wetmore, Cynthia, Davies, James A, Parker, Alan L, Evgin, Laura, Vile, Richard G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746943/
https://www.ncbi.nlm.nih.gov/pubmed/32459315
http://dx.doi.org/10.1093/neuonc/noaa126

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7746943/
https://www.ncbi.nlm.nih.gov/pubmed/32459315
http://dx.doi.org/10.1093/neuonc/noaa126

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