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Effect of Once-Weekly Azithromycin vs Placebo in Children With HIV-Associated Chronic Lung Disease: The BREATHE Randomized Clinical Trial

IMPORTANCE: HIV-associated chronic lung disease (HCLD) in children is associated with small airways disease, is common despite antiretroviral therapy (ART), and is associated with substantial morbidity. Azithromycin has antibiotic and immunomodulatory activity and may be effective in treating HCLD t...

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Detalles Bibliográficos
Autores principales: Ferrand, Rashida A., McHugh, Grace, Rehman, Andrea M., Mujuru, Hilda, Simms, Victoria, Majonga, Edith D., Nicol, Mark P., Flaegstad, Trond, Gutteberg, Tore J., Gonzalez-Martinez, Carmen, Corbett, Elizabeth L., Rowland-Jones, Sarah L., Kranzer, Katharina, Weiss, Helen A., Odland, Jon O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747021/
https://www.ncbi.nlm.nih.gov/pubmed/33331916
http://dx.doi.org/10.1001/jamanetworkopen.2020.28484