Altered Basal Autophagy Affects Extracellular Vesicle Release in Cells of Lagotto Romagnolo Dogs With a Variant ATG4D

Lagotto Romagnolo breed dogs develop a progressive neurological disease with intracellular vacuolar storage when homozygous for a variant in the autophagy-related gene 4D (ATG4D). A lysosomal enzyme deficiency has not been proven in this disease, despite its overlapping morphology with lysosomal sto...

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Detalles Bibliográficos
Autores principales: Syrjä, Pernilla, Palviainen, Mari, Jokinen, Tarja, Kyöstilä, Kaisa, Lohi, Hannes, Roosje, Petra, Anderegg, Linda, Leeb, Tosso, Sukura, Antti, Eskelinen, Eeva-Liisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Animal Models of Human Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747043/
https://www.ncbi.nlm.nih.gov/pubmed/33016245
http://dx.doi.org/10.1177/0300985820959243

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747043/
https://www.ncbi.nlm.nih.gov/pubmed/33016245
http://dx.doi.org/10.1177/0300985820959243

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