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Alteration of serum amino acid profiles by dietary adenine supplementation inhibits fatty liver development in rats

Studies on animal models have demonstrated that feeding a low-arginine diet inhibits triacylglycerol (TAG) secretion from the liver, resulting in marked fatty liver development in rats. Here, we first showed that culturing hepatocytes in the medium mimicking the serum amino acid profile of low-argin...

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Detalles Bibliográficos
Autores principales: Nishi, Hiroki, Yamanaka, Daisuke, Masuda, Masato, Goda, Yuki, Ito, Koichi, Hakuno, Fumihiko, Takahashi, Shin-Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747621/
https://www.ncbi.nlm.nih.gov/pubmed/33335253
http://dx.doi.org/10.1038/s41598-020-79234-w