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Alteration of serum amino acid profiles by dietary adenine supplementation inhibits fatty liver development in rats
Studies on animal models have demonstrated that feeding a low-arginine diet inhibits triacylglycerol (TAG) secretion from the liver, resulting in marked fatty liver development in rats. Here, we first showed that culturing hepatocytes in the medium mimicking the serum amino acid profile of low-argin...
Autores principales: | Nishi, Hiroki, Yamanaka, Daisuke, Masuda, Masato, Goda, Yuki, Ito, Koichi, Hakuno, Fumihiko, Takahashi, Shin-Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747621/ https://www.ncbi.nlm.nih.gov/pubmed/33335253 http://dx.doi.org/10.1038/s41598-020-79234-w |
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