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DNA aptamer-based rolling circle amplification product as a novel immunological adjuvant

Several agonists to CD40 have shown to induce acquired immune responses. Here, we developed and evaluated the rolling circle amplification (RCA) products that are based on anti-CD40 DNA aptamers as a novel vaccine adjuvant. First, we developed DNA aptamers with specific binding affinity to chicken C...

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Detalles Bibliográficos
Autores principales: Al-Ogaili, Adil S., Liyanage, Rohana, Lay, Jack O., Jiang, Tieshan, Vuong, Christine N., Agrawal, Shilpi, Kumar, Thallapuranam Krishnaswamy Suresh, Berghman, Luc R., Hargis, Billy M., Kwon, Young Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747709/
https://www.ncbi.nlm.nih.gov/pubmed/33335251
http://dx.doi.org/10.1038/s41598-020-79420-w