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Epigenetic differences at the HTR2A locus in progressive multiple sclerosis patients

The pathology of progressive multiple sclerosis (MS) is poorly understood. We have previously assessed DNA methylation in the CD4(+) T cells of relapsing–remitting (RR) MS patients compared to healthy controls and identified differentially methylated regions (DMRs) in HLA-DRB1 and RNF39. This study...

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Detalles Bibliográficos
Autores principales: Maltby, Vicki E., Lea, Rodney A., Burnard, Sean, Xavier, Alexandre, Van Cao, Thao, White, Nicole, Kennedy, Daniel, Groen, Kira, Sanders, Katherine A., Seeto, Rebecca, Bray, Samara, Gresle, Melissa, Laverick, Louise, Butzkueven, Helmut, Scott, Rodney J., Lechner-Scott, Jeannette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747721/
https://www.ncbi.nlm.nih.gov/pubmed/33335118
http://dx.doi.org/10.1038/s41598-020-78809-x