Cargando…
Epigenetic differences at the HTR2A locus in progressive multiple sclerosis patients
The pathology of progressive multiple sclerosis (MS) is poorly understood. We have previously assessed DNA methylation in the CD4(+) T cells of relapsing–remitting (RR) MS patients compared to healthy controls and identified differentially methylated regions (DMRs) in HLA-DRB1 and RNF39. This study...
Autores principales: | Maltby, Vicki E., Lea, Rodney A., Burnard, Sean, Xavier, Alexandre, Van Cao, Thao, White, Nicole, Kennedy, Daniel, Groen, Kira, Sanders, Katherine A., Seeto, Rebecca, Bray, Samara, Gresle, Melissa, Laverick, Louise, Butzkueven, Helmut, Scott, Rodney J., Lechner-Scott, Jeannette |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747721/ https://www.ncbi.nlm.nih.gov/pubmed/33335118 http://dx.doi.org/10.1038/s41598-020-78809-x |
Ejemplares similares
-
Letter to the editor: blood processing and sample storage have negligible effects on methylation
por: Groen, Kira, et al.
Publicado: (2018) -
Erythrocyte microRNAs show biomarker potential and implicate multiple sclerosis susceptibility genes
por: Groen, Kira, et al.
Publicado: (2020) -
Erythrocytes in multiple sclerosis – forgotten contributors to the
pathophysiology?
por: Groen, Kira, et al.
Publicado: (2016) -
Erythrocyte microRNA sequencing reveals differential expression in relapsing-remitting multiple sclerosis
por: Groen, Kira, et al.
Publicado: (2018) -
Whole-blood methylation signatures are associated with and accurately classify multiple sclerosis disease severity
por: Campagna, Maria Pia, et al.
Publicado: (2022)