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Association of the polymorphism Exon 1 (A/O) region of the mannose-binding lectin gene and periportal fibrosis regression in schistosomiasis after specific treatment

INTRODUCTION: We evaluated the association between genetic polymorphisms in exon 1 (A/O alleles) and promoter regions at positions -550 (H/L variant, rs11003125) and -221 (X/Y variant, rs7096206) MBL2 and periportal fibrosis regression. METHODS: This was a retrospective cohort study involving 114 Br...

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Detalles Bibliográficos
Autores principales: de Oliveira, Saulo Gomes, de Souza, Ilana Brito Ferraz, Constantino, Taynan da Silva, Silva, Paula Carolina Valença, de Lima, Elker Lene Santos, Muniz, Maria Tereza Cartaxo, Domingues, Ana Lúcia Coutinho
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747812/
https://www.ncbi.nlm.nih.gov/pubmed/33338108
http://dx.doi.org/10.1590/0037-8682-0145-2020