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Comparative genomic analysis of primary tumors and paired brain metastases in lung cancer patients by whole exome sequencing: a pilot study

Lung cancer brain metastases (BMs) are frequent and associated with poor prognosis despite a better knowledge of lung cancer biology and the development of targeted therapies. The inconstant intracranial response to systemic treatments is partially due to tumor heterogeneity between the primary lung...

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Detalles Bibliográficos
Autores principales: Tomasini, Pascale, Barlesi, Fabrice, Gilles, Sophie, Nanni-Metellus, Isabelle, Soffietti, Riccardo, Denicolai, Emilie, Pellegrino, Eric, Bialecki, Emilie, Ouafik, L’Houcine, Metellus, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747858/
https://www.ncbi.nlm.nih.gov/pubmed/33400739
http://dx.doi.org/10.18632/oncotarget.27837