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Development of Plant Prime-Editing Systems for Precise Genome Editing

Prime-editing systems have the capability to perform efficient and precise genome editing in human cells. In this study, we first developed a plant prime editor 2 (pPE2) system and test its activity by generating a targeted mutation on an HPT(-ATG) reporter in rice. Our results showed that the pPE2...

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Detalles Bibliográficos
Autores principales: Xu, Rongfang, Li, Juan, Liu, Xiaoshuang, Shan, Tiaofeng, Qin, Ruiying, Wei, Pengcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7747961/
https://www.ncbi.nlm.nih.gov/pubmed/33367239
http://dx.doi.org/10.1016/j.xplc.2020.100043