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OGG1 DNA Repair Gene Polymorphism As a Biomarker of Oxidative and Genotoxic DNA Damage

BACKGROUND: Single nucleotide polymorphisms in OGG1 gene modulates DNA repair capacity and functions as one of the first lines of protective mechanisms against 8-OHdG mutagenicity. OGG1-Cys326 gene polymorphism may decrease DNA repair function, causing oxidative stress due to higher oxidative DNA da...

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Detalles Bibliográficos
Autores principales: Miglani, Kanika, Kumar, Sunil, Yadav, Anita, Aggarwal, Neeraj, Gupta, Ranjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pasteur Institute of Iran 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748119/
https://www.ncbi.nlm.nih.gov/pubmed/33129239
http://dx.doi.org/10.29252/ibj.25.1.47