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Genetically increased circulating 25(OH)D level reduces the risk of type 2 diabetes in subjects with deficiency of vitamin D: A large-scale Mendelian randomization study

Observational studies have reported that Vitamin D deficiency and the risk type 2 diabetes are associated, but the causation is unclear. Mendelian randomization (MR) involving genetic variants as instrument variables (IVs) overcomes the reverse-casualty and unmeasured confounding. However, with limi...

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Detalles Bibliográficos
Autores principales: Xu, Yingying, Zhou, Yuan, Liu, Jingjing, Wang, Chenfang, Qu, Zhongjie, Wei, Zhili, Zhou, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748166/
https://www.ncbi.nlm.nih.gov/pubmed/33371106
http://dx.doi.org/10.1097/MD.0000000000023672