A small molecule that mitigates bacterial infection disrupts Gram-negative cell membranes and is inhibited by cholesterol and neutral lipids

Infections caused by Gram-negative bacteria are difficult to fight because these pathogens exclude or expel many clinical antibiotics and host defense molecules. However, mammals have evolved a substantial immune arsenal that weakens pathogen defenses, suggesting the feasibility of developing therap...

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Detalles Bibliográficos
Autores principales: Dombach, Jamie L., Quintana, Joaquin L. J., Nagy, Toni A., Wan, Chun, Crooks, Amy L., Yu, Haijia, Su, Chih-Chia, Yu, Edward W., Shen, Jingshi, Detweiler, Corrella S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748285/
https://www.ncbi.nlm.nih.gov/pubmed/33290418
http://dx.doi.org/10.1371/journal.ppat.1009119

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7748285/
https://www.ncbi.nlm.nih.gov/pubmed/33290418
http://dx.doi.org/10.1371/journal.ppat.1009119

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