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Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo.

Dysregulated neutrophil (PMN) transmigration across epithelial surfaces (TEpM) significantly contributes to chronic inflammatory diseases, yet mechanisms defining this process remain poorly understood. In the intestine, uncontrolled PMN TEpM is a hallmark of disease flares in ulcerative colitis. Pre...

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Detalles Bibliográficos
Autores principales: Azcutia, Veronica, Kelm, Matthias, Luissint, Anny-Claude, Boerner, Kevin, Flemming, Sven, Quiros, Miguel, Newton, Gail, Nusrat, Asma, Luscinskas, Francis W., Parkos, Charles A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749029/
https://www.ncbi.nlm.nih.gov/pubmed/32561828
http://dx.doi.org/10.1038/s41385-020-0316-4