Cortical bone adaptation to a moderate level of mechanical loading in male Sost deficient mice

Loss-of-function mutations in the Sost gene lead to high bone mass phenotypes. Pharmacological inhibition of Sost/sclerostin provides a new drug strategy for treating osteoporosis. Questions remain as to how physical activity may affect bone mass under sclerostin inhibition and if that effect differ...

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Detalles Bibliográficos
Autores principales: Yang, Haisheng, Büttner, Alexander, Albiol, Laia, Julien, Catherine, Thiele, Tobias, Figge, Christine, Kramer, Ina, Kneissel, Michaela, Duda, Georg N., Checa, Sara, Willie, Bettina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749116/
https://www.ncbi.nlm.nih.gov/pubmed/33339872
http://dx.doi.org/10.1038/s41598-020-79098-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749116/
https://www.ncbi.nlm.nih.gov/pubmed/33339872
http://dx.doi.org/10.1038/s41598-020-79098-0

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