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Functional annotation of genetic associations by transcriptome-wide association analysis provides insights into neutrophil development regulation

Genome-wide association studies (GWAS) have identified multiple genomic loci linked to blood cell traits, however understanding the biological relevance of these genetic loci has proven to be challenging. Here, we performed a transcriptome-wide association study (TWAS) integrating gene expression an...

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Detalles Bibliográficos
Autores principales: Yao, Yao, Yang, Jia, Qin, Qian, Tang, Chao, Li, Zhidan, Chen, Li, Li, Kailong, Ren, Chunyan, Chen, Lu, Rao, Shuquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749173/
https://www.ncbi.nlm.nih.gov/pubmed/33340029
http://dx.doi.org/10.1038/s42003-020-01527-7