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Functional expression of human prostaglandin E2 receptor 4 (EP4) in E. coli and characterization of the binding property of EP4 with G(α) proteins

Human prostaglandin E2 receptor 4 (EP4) is one of the four subtypes of prostaglandin E(2) (PGE(2)) receptors and belongs to the rhodopsin-type G protein-coupled receptor (GPCR) family. Particularly, EP4 is expressed in various cancer cells and is involved in cancer-cell proliferation by a G protein...

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Detalles Bibliográficos
Autores principales: Kim, Nam Hyuk, Kim, Key-Sun, Shin, Sang Chul, Kim, Eunice Eunkyeong, Yu, Yeon Gyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749421/
https://www.ncbi.nlm.nih.gov/pubmed/33367116
http://dx.doi.org/10.1016/j.bbrep.2020.100871