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Motoneuron deafferentation and gliosis occur in association with neuromuscular regressive changes during ageing in mice

BACKGROUND: The cellular mechanisms underlying the age‐associated loss of muscle mass and function (sarcopenia) are poorly understood, hampering the development of effective treatment strategies. Here, we performed a detailed characterization of age‐related pathophysiological changes in the mouse ne...

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Detalles Bibliográficos
Autores principales: Blasco, Alba, Gras, Sílvia, Mòdol‐Caballero, Guillem, Tarabal, Olga, Casanovas, Anna, Piedrafita, Lídia, Barranco, Alejandro, Das, Tapas, Pereira, Suzette L., Navarro, Xavier, Rueda, Ricardo, Esquerda, Josep E., Calderó, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749545/
https://www.ncbi.nlm.nih.gov/pubmed/32691534
http://dx.doi.org/10.1002/jcsm.12599