Cargando…
Brain metabolites in cholinergic and glutamatergic pathways are altered by pancreatic cancer cachexia
BACKGROUND: Cachexia is a major cause of morbidity in pancreatic ductal adenocarcinoma (PDAC) patients. Our purpose was to understand the impact of PDAC‐induced cachexia on brain metabolism in PDAC xenograft studies, to gain new insights into the causes of cachexia‐induced morbidity. Changes in mous...
Autores principales: | Winnard, Paul T., Bharti, Santosh Kumar, Sharma, Raj Kumar, Krishnamachary, Balaji, Mironchik, Yelena, Penet, Marie‐France, Goggins, Michael G., Maitra, Anirban, Kamel, Ihab, Horton, Karen M., Jacobs, Michael A., Bhujwalla, Zaver M. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749557/ https://www.ncbi.nlm.nih.gov/pubmed/33006443 http://dx.doi.org/10.1002/jcsm.12621 |
Ejemplares similares
-
Metabolic consequences of HIF silencing in a triple negative human breast cancer xenograft
por: Bharti, Santosh K., et al.
Publicado: (2018) -
The PD-L1 metabolic interactome intersects with choline metabolism and inflammation
por: Pacheco-Torres, Jesus, et al.
Publicado: (2021) -
PD-L1 siRNA Theranostics With a Dextran Nanoparticle Highlights the Importance of Nanoparticle Delivery for Effective Tumor PD-L1 Downregulation
por: Pacheco-Torres, Jesus, et al.
Publicado: (2021) -
Hypoxia theranostics of a human prostate cancer xenograft and the resulting effects on the tumor microenvironment
por: Krishnamachary, Balaji, et al.
Publicado: (2020) -
Combining Optical Reporter Proteins with Different Half-lives to Detect Temporal Evolution of Hypoxia and Reoxygenation in Tumors
por: Danhier, Pierre, et al.
Publicado: (2015)