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Safety and pharmacokinetics of bimagrumab in healthy older and obese adults with body composition changes in the older cohort

BACKGROUND: Bimagrumab prevents activity of myostatin and other negative regulators of skeletal muscle mass. This randomized double‐blind, placebo‐controlled study investigated safety, pharmacokinetics (PK), and pharmacodynamics of bimagrumab in healthy older and obese adults. METHODS: A cohort of o...

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Detalles Bibliográficos
Autores principales: Rooks, Daniel, Petricoul, Olivier, Praestgaard, Jens, Bartlett, Michael, Laurent, Didier, Roubenoff, Ronenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749589/
https://www.ncbi.nlm.nih.gov/pubmed/33264516
http://dx.doi.org/10.1002/jcsm.12639