Inhibition of tumor suppressor p73 by nerve growth factor receptor via chaperone-mediated autophagy

The tumor suppressr p73 is a homolog of p53 and is capable of inducing cell cycle arrest and apoptosis. Here, we identify nerve growth factor receptor (NGFR, p75NTR, or CD271) as a novel negative p73 regulator. p73 activates NGFR transcription, which, in turn, promotes p73 degradation in a negative...

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Detalles Bibliográficos
Autores principales: Nguyen, Daniel, Yang, Kun, Chiao, Lucia, Deng, Yun, Zhou, Xiang, Zhang, Zhen, Zeng, Shelya X, Lu, Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749740/
https://www.ncbi.nlm.nih.gov/pubmed/32285119
http://dx.doi.org/10.1093/jmcb/mjaa017

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749740/
https://www.ncbi.nlm.nih.gov/pubmed/32285119
http://dx.doi.org/10.1093/jmcb/mjaa017

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