MDMX phosphorylation-dependent p53 downregulation contributes to an immunosuppressive tumor microenvironment

A role of tumor-suppressive activity of p53 in the tumor microenvironment (TME) has been implicated but remains fairly understudied. To address this knowledge gap, we leveraged our Mdmx(S314A) mice as recipients to investigate how implanted tumor cells incapacitate host p53 creating a conducive TME...

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Detalles Bibliográficos
Autores principales: Wang, Bing, Lim, Chuan-Bian, Yan, Jiawei, Li, Lizhen, Wang, Jufang, Little, John B, Yuan, Zhi-Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749742/
https://www.ncbi.nlm.nih.gov/pubmed/32706867
http://dx.doi.org/10.1093/jmcb/mjaa038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7749742/
https://www.ncbi.nlm.nih.gov/pubmed/32706867
http://dx.doi.org/10.1093/jmcb/mjaa038

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