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Potential roles of mitochondrial cofactors in the adjuvant mitigation of proinflammatory acute infections, as in the case of sepsis and COVID-19 pneumonia

BACKGROUND: The mitochondrial cofactors α-lipoic acid (ALA), coenzyme Q10 (CoQ10) and carnitine (CARN) play distinct and complementary roles in mitochondrial functioning, along with strong antioxidant actions. Also termed mitochondrial nutrients (MNs), these cofactors have demonstrated specific prot...

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Detalles Bibliográficos
Autores principales: Pagano, Giovanni, Manfredi, Carla, Pallardó, Federico V., Lyakhovich, Alex, Tiano, Luca, Trifuoggi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750159/
https://www.ncbi.nlm.nih.gov/pubmed/33346851
http://dx.doi.org/10.1007/s00011-020-01423-0