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SOX2-Upregulated microRNA-30e Promotes the Progression of Esophageal Cancer via Regulation of the USP4/SMAD4/CK2 Axis

Esophageal cancer (EC) is a highly aggressive disease, and its progression involves a complex gene regulation network. Transcription factor SOX2 is amplified in various cancers including EC. A pathway involving SOX2 regulation of microRNAs (miRNAs) and their target genes has been previously revealed...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Fan, Xin, Ren, Yukai, Wu, Kai, Tian, Xiangyu, Wen, Fengbiao, Liu, Donglei, Fan, Yuxia, Zhao, Song
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750169/
https://www.ncbi.nlm.nih.gov/pubmed/33376627
http://dx.doi.org/10.1016/j.omtn.2020.10.027