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Slow Transition Path Times Reveal a Complex Folding Barrier in a Designed Protein
De-novo designed proteins have received wide interest as potential platforms for nano-engineering and biomedicine. While much work is being done in the design of thermodynamically stable proteins, the folding process of artificially designed proteins is not well-studied. Here we used single-molecule...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750197/ https://www.ncbi.nlm.nih.gov/pubmed/33365300 http://dx.doi.org/10.3389/fchem.2020.587824 |