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Key Metabolic Pathways in MSC-Mediated Immunomodulation: Implications for the Prophylaxis and Treatment of Graft Versus Host Disease

Mesenchymal stromal cells (MSCs) are spindle-shaped, plastic-adherent cells in vitro with potent immunosuppressive activity both in vitro and in vivo. MSCs have been employed as a cellular immunotherapy in diverse preclinical models and clinical trials, but most commonly as agents for the prophylaxi...

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Detalles Bibliográficos
Autores principales: Burnham, Andre J., Foppiani, Elisabetta Manuela, Horwitz, Edwin M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750397/
https://www.ncbi.nlm.nih.gov/pubmed/33365034
http://dx.doi.org/10.3389/fimmu.2020.609277