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Optical clearing of living brains with MAGICAL to extend in vivo imaging

To understand brain functions, it is important to observe directly how multiple neural circuits are performing in living brains. However, due to tissue opaqueness, observable depth and spatiotemporal resolution are severely degraded in vivo. Here, we propose an optical brain clearing method for in v...

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Detalles Bibliográficos
Autores principales: Iijima, Kouichirou, Oshima, Takuto, Kawakami, Ryosuke, Nemoto, Tomomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750414/
https://www.ncbi.nlm.nih.gov/pubmed/33364578
http://dx.doi.org/10.1016/j.isci.2020.101888