Determining homologous recombination deficiency scores with whole exome sequencing and their association with responses to neoadjuvant chemotherapy in breast cancer

Recent studies demonstrated that homologous repair deficiency (HRD) score is a useful marker for response to poly (ADP-ribose) polymerase inhibitors or platinum-based chemotherapy. We determined HRD scores and elucidated the clinicopathologic characteristics of HRD-high tumors and their response to...

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Detalles Bibliográficos
Autores principales: Kim, Seung Jin, Sota, Yoshiaki, Naoi, Yasuto, Honma, Keiichiro, Kagara, Naofumi, Miyake, Tomohiro, Shimoda, Masafumi, Tanei, Tomonori, Seno, Shigeto, Matsuda, Hideo, Noguchi, Shinzaburo, Shimazu, Kenzo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750421/
https://www.ncbi.nlm.nih.gov/pubmed/33340887
http://dx.doi.org/10.1016/j.tranon.2020.100986

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750421/
https://www.ncbi.nlm.nih.gov/pubmed/33340887
http://dx.doi.org/10.1016/j.tranon.2020.100986

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