Essentially Leading Antibody Production: An Investigation of Amino Acids, Myeloma, and Natural V-Region Signal Peptides in Producing Pertuzumab and Trastuzumab Variants

Boosting the production of recombinant therapeutic antibodies is crucial in both academic and industry settings. In this work, we investigated the usage of varying signal peptides by antibody V-genes and their roles in recombinant transient production, systematically comparing myeloma and the native...

Descripción completa

Detalles Bibliográficos
Autores principales: Ling, Wei-Li, Su, Chinh Tran-To, Lua, Wai-Heng, Poh, Jun-Jie, Ng, Yuen-Ling, Wipat, Anil, Gan, Samuel Ken-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750424/
https://www.ncbi.nlm.nih.gov/pubmed/33365032
http://dx.doi.org/10.3389/fimmu.2020.604318

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750424/
https://www.ncbi.nlm.nih.gov/pubmed/33365032
http://dx.doi.org/10.3389/fimmu.2020.604318

Ejemplares similares