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Thrombospondin-1 Receptor CD47 Overexpression Contributes to P-Glycoprotein-Mediated Multidrug Resistance Against Doxorubicin in Thyroid Carcinoma FTC-133 Cells

It is now admitted that in addition to acquired resistance, the tumor microenvironment contributes to the development of chemo-resistance and malignant progression. In a previous study, we showed that Dox induced apoptosis in FTC-133 cells by trigging JNK pathway. This process was accompanied by a d...

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Detalles Bibliográficos
Autores principales: Courageot, Marie-Pierre, Duca, Laurent, Martiny, Laurent, Devarenne-Charpentier, Emmanuelle, Morjani, Hamid, El Btaouri, Hassan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750475/
https://www.ncbi.nlm.nih.gov/pubmed/33365267
http://dx.doi.org/10.3389/fonc.2020.551228