Acetoacetate enhancement of glucose mediated DNA glycation

Acetoacetate (AA) is a ketone body, which generates reactive oxygen species (ROS). ROS production is impacted by the formation of covalent bonds between amino groups of biomacromolecules and reducing sugars (glycation). Glycation can damage DNA by causing strand breaks, mutations, and changes in gen...

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Detalles Bibliográficos
Autores principales: Bagherzadeh-Yazdi, M., Bohlooli, M., Khajeh, M., Ghamari, F., Ghaffari-Moghaddam, M., Poormolaie, N., Khatibi, A., Hasanein, P., Sheibani, N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750490/
https://www.ncbi.nlm.nih.gov/pubmed/33364448
http://dx.doi.org/10.1016/j.bbrep.2020.100878

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750490/
https://www.ncbi.nlm.nih.gov/pubmed/33364448
http://dx.doi.org/10.1016/j.bbrep.2020.100878

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