Modulation of the liver immune microenvironment by the adeno-associated virus serotype 8 gene therapy vector

Adeno-associated viruses (AAVs) are emerging as one of the vehicles of choice for gene therapy. However, the potential immunogenicity of these vectors is a major limitation of their use, leading to the necessity of a better understanding of how viral vectors engage the innate immune system. In this...

Descripción completa

Detalles Bibliográficos
Autores principales: Carestia, Agostina, Kim, Seok-Joo, Horling, Franziska, Rottensteiner, Hanspeter, Lubich, Christian, Reipert, Birgit M., Crowe, Brian A., Jenne, Craig N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750493/
https://www.ncbi.nlm.nih.gov/pubmed/33376758
http://dx.doi.org/10.1016/j.omtm.2020.10.023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750493/
https://www.ncbi.nlm.nih.gov/pubmed/33376758
http://dx.doi.org/10.1016/j.omtm.2020.10.023

Ejemplares similares