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Differences in fungal immune recognition by monocytes and macrophages: N-mannan can be a shield or activator of immune recognition

We designed experiments to assess whether fungal cell wall mannans function as an immune shield or an immune agonist. Fungal cell wall β-(1,3)-glucan normally plays a major and dominant role in immune activation. The outer mannan layer has been variously described as an immune shield, because it has...

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Detalles Bibliográficos
Autores principales: Yadav, Bhawna, Mora-Montes, Héctor M., Wagener, Jeanette, Cunningham, Iain, West, Lara, Haynes, Ken, Brown, Alistair J.P., Gow, Neil A.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750734/
https://www.ncbi.nlm.nih.gov/pubmed/33364531
http://dx.doi.org/10.1016/j.tcsw.2020.100042