Enhanced lysosome escape mediated by 1,2-dicarboxylic-cyclohexene anhydride-modified poly-l-lysine dendrimer as a gene delivery system

Antisense oligodeoxynucleotide (ASODN) can directly interfere a series of biological events of the target RNA derived from tumor cells through Watson-Crick base pairing, in turn, plays antitumor therapeutic roles. In the study, a novel HIF-1α ASODN-loaded nanocomposite was formulated to efficiently...

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Detalles Bibliográficos
Autores principales: Shen, Jianmin, Chen, Jing, Ma, Jingbo, Fan, Linlan, Zhang, Xiaoli, Yue, Ting, Yan, Yaping, Zhang, Yuhang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Shenyang Pharmaceutical University 2020
Materias:
Original Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750821/
https://www.ncbi.nlm.nih.gov/pubmed/33363631
http://dx.doi.org/10.1016/j.ajps.2019.12.001

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7750821/
https://www.ncbi.nlm.nih.gov/pubmed/33363631
http://dx.doi.org/10.1016/j.ajps.2019.12.001

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